Sanne J. Christiansen

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Histone deacetylase inhibitors (HDACi) inhibit the growth of cancer cells, and combinations of HDACi with established chemotherapeutics can lead to synergistic effects. We have investigated effects of PXD101 (HDACi in phase II clinical trials) in combination with 5-fluorouracil, on tumour cell proliferation and apoptosis both in vitro and in vivo. HCT116(More)
INTRODUCTION Child homicides are rare but serious crimes. In this study the homicide rate and the development in the crime pattern will be investigated. MATERIAL AND METHODS The investigation is retrospective and comprises the 34 years during which the Institute of Forensic Medicine in Odense has existed. During this period 41 children under the age of 15(More)
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