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Accelerometer based gesture control is proposed as a complementary interaction modality for handheld devices. Predetermined gesture commands or freely trainable by the user can be used for controlling functions also in other devices. To support versatility of gesture commands in various types of personal device applications gestures should be customisable,(More)
The antitumor effects of a new antiestrogen, Fc-1157a have been studied in vitro and in vivo. In vitro the effect of Fc-1157a was comparable to that of tamoxifen. The effect was dose-dependent, and at concentrations higher than 10(-6) mol/1 Fc-1157a induced real cell death of the MCF-7 cells. In DMBA-induced mammary cancer in rats Fc-1157a decreased the(More)
The basic pharmacological and biochemical properties of a new antiestrogen, Fc-1157a, are described. Fc-1157a is bound specifically and with high affinity to estrogen receptors. The binding is competitive with estradiol. Fc-1157a treatment induces translocation of estrogen receptors from cytoplasm to nucleus. The turnover rate of nuclear estrogen receptors(More)
OBJECTIVE To compare the effects of continuous use of oral (OC), transdermal, and vaginal combined contraceptives on the pituitary-ovarian axis and inhibition of follicular development. DESIGN Spin-off study of a prospective, randomized trial. SETTING University clinic. PATIENT(S) Forty-two of 54 healthy women completed the study. INTERVENTION(S)(More)
CONTEXT Postnatal pituitary-testicular activation in infant boys is well characterized. However, the ovarian response to pituitary activation in infancy is less well understood. OBJECTIVE The aim of the study was to compare postnatal developmental changes in the pituitary-ovarian axis in preterm and term infant girls. PARTICIPANTS AND DESIGN Sixty-three(More)
A placebo-controlled, double-blind study was conducted to investigate the effects of seed and pulp oils of sea buckthorn (Hipphophae rhamnoides) on atopic dermatitis. Linoleic (34%), alpha-linolenic (25%), and oleic (19%) acids were the major fatty acids in the seed oil, whereas palmitic (33%), oleic (26%), and palmitoleic (25%) acids were the major fatty(More)