Sankareswaran Senthilkumar

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Ambient particulate matter (PM) collected in the vicinity of five industries (Cement, Chemical, Thermal power plant, Sponge-iron and Steel) in Tamil Nadu state, India was characterized for size distribution, metals and polycyclic aromatic hydrocarbons (PAHs) content. Genotoxicity of PM and organic matter (OM) extracted from PM was measured in human lung(More)
Microorganisms play an important role in the bioconversion and total breakdown of pesticides in the environment. This study was conducted to assess the pesticide degradation (endosulfan and methyl parathion) ability of the bacteria and fungi (Pseudomonas aeruginosa and Trichoderma viridae). The screening test conducted to reveal the ability to degrade(More)
The aim of this study is to investigate a new strategy of combined application of ZnO/PEG nanospheres with anticancer drug of doxorubicin (DOX) in photodynamic therapy (PDT). We were able to fabricate ZnO/PEG nanospheres as the drug carrier of DOX in drug delivery system. The combination of DOX-ZnO/PEG nanocomposites induced the remarkable improvement in(More)
In the present investigation, aqueous, ethanol and petroleum ether, ethanol (1:1) root extracts of Seidenfia rheedii were tested against 12 different human pathogenic bacteria for antibacterial activity. It was found that ethanolic extracts inhibited the growth of all the bacterial strains tested whereas moderate antibacterial activity was associated with(More)
The multi-industrial applications of zinc oxide nanomaterials (ZnO NMs) lead to increasing exposure to humans. Though the ZnO nanoparticles (NPs) toxicity had been evaluated previously, toxicity of other forms of ZnO nanomaterials has not been evaluated. In this study, cytotoxicity and genotoxicity of four different types of ZnO NMs were evaluated using(More)
Oxidative stress is an important factor contributing to the pathogenesis of diabetes and its complications. In our earlier study, we demonstrated the antidiabetic efficacy of morin by regulating key enzymes of carbohydrate metabolism in diabetic rats. The present study was designed to assess the antigenotoxic potential of morin in pancreatic β-cells, using(More)
The salubrious effects of 3-Formylchromone (3-FC) against nitrosodiethylamine (NDEA) mediated early hepatocellular carcinogenesis was investigated in vivo by this study. Male Wistar rats were administered three interspersed intraperitoneal injections of NDEA (200 mg/kg body weight) until sixth week, followed by, thrice a week oral dose of 3-FC (25 mg/kg(More)
Size- and charge-selective ion transfer across the zeolite-Y-modified interface between two immiscible electrolyte solutions (ZM-ITIES) is described. The zeolite-Y membrane is prepared from pressed disks by healing with tetraethyl orthosilicate (TEOS). Size- and charge-selective transfer of the tetraethylammonium cation, size-selective exclusion of(More)
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