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- Publications
- Influence
Cancer stem cells: therapeutic implications and perspectives in cancer therapy
- L. Han, Sanjun Shi, T. Gong, Zhirong Zhang, Xun Sun
- Medicine
- 1 April 2013
Abstract The cancer stem cell (CSC) theory is gaining increasing attention from researchers and has become an important focus of cancer research. According to the theory, a minority population of… Expand
A Novel Top-Down Synthesis of Ultrathin 2D Boron Nanosheets for Multimodal Imaging-Guided Cancer Therapy.
- Xiaoyuan Ji, Na Kong, +13 authors J. Shi
- Materials Science, Medicine
- Advanced materials
- 1 September 2018
Single atom nonmetal 2D nanomaterials have shown considerable potential in cancer nanomedicines, owing to their intriguing properties and biocompatibility. Herein, ultrathin boron nanosheets (B NSs)… Expand
Dual drugs (microRNA-34a and paclitaxel)-loaded functional solid lipid nanoparticles for synergistic cancer cell suppression.
- Sanjun Shi, Lu Han, +5 authors Xun Sun
- Medicine
- Journal of controlled release : official journal…
- 28 November 2014
A co-delivery system that can transport cancer related microRNAs and chemotherapeutics to their distinct targets in the tumors is an attractive strategy to eliminate tumor relapse in lung cancer… Expand
Preparation, characterization, and in vivo evaluation of a self-nanoemulsifying drug delivery system (SNEDDS) loaded with morin-phospholipid complex
- Jinjie Zhang, Q. Peng, +4 authors Z. Zhang
- Materials Science, Medicine
- International journal of nanomedicine
- 19 December 2011
Background As a poorly water-soluble drug, the oral application of morin is limited by its low oral bioavailability. In this study, a new self-nanoemulsifying drug delivery system (SNEDDS), based on… Expand
Coating Solid Lipid Nanoparticles with Hyaluronic Acid Enhances Antitumor Activity against Melanoma Stem-like Cells
- Hongxin Shen, Sanjun Shi, Z. Zhang, T. Gong, X. Sun
- Biology, Medicine
- Theranostics
- 5 April 2015
Successful anticancer chemotherapy requires targeting tumors efficiently and further potential to eliminate cancer stem cell (CSC) subpopulations. Since CD44 is present on many types of CSCs, and it… Expand
Enhanced antitumor response mediated by the codelivery of paclitaxel and adenoviral vector expressing IL-12.
- Linjie Cao, Qin Zeng, C. Xu, Sanjun Shi, Z. Zhang, X. Sun
- Chemistry, Medicine
- Molecular pharmaceutics
- 16 April 2013
It has been well-established that chemo-immunotherapy using cytotoxic drugs and appropriate cytokines offers a promising approach for the treatment of neoplastic diseases. In view of this, to improve… Expand
An in situ-forming phospholipid-based phase transition gel prolongs the duration of local anesthesia for ropivacaine with minimal toxicity.
- Hanmei Li, T. Liu, +5 authors Sanjun Shi
- Materials Science, Medicine
- Acta biomaterialia
- 1 August 2017
An injectable, phospholipid-based phase transition gel (PPTG) has been developed for prolonging the release of ropivacaine (RO) for local anesthesia. PPTG was prepared by mixing phospholipids,… Expand
Anionic liposomes increase the efficiency of adenovirus-mediated gene transfer to coxsackie-adenovirus receptor deficient cells.
- Zhirong Zhong, Sanjun Shi, J. Han, Zhirong Zhang, X. Sun
- Biology, Medicine
- Molecular pharmaceutics
- 1 February 2010
Despite remarkable progress in the research of both viral and nonviral gene delivery vectors, the drawbacks in each delivery system have limited their clinical applications. Therefore, one of the… Expand
Circulating Tumor Cells: From Theory to Nanotechnology-Based Detection
- Yue Ming, Yuanyuan Li, +5 authors Sanjun Shi
- Medicine
- Front. Pharmacol.
- 1 February 2017
Cancer stem cells with stem-cell properties are regarded as tumor initiating cells. Sharing stem-cell properties, circulating tumor cells (CTCs) are responsible for the development of metastasis,… Expand
Specific cancer stem cell-therapy by albumin nanoparticles functionalized with CD44-mediated targeting
- Y. Li, Sanjun Shi, +6 authors Jian-hong Chen
- Medicine, Biology
- Journal of Nanobiotechnology
- 1 December 2018
BackgroundCancer stem cells (CSCs) are highly proliferative and tumorigenic, which contributes to chemotherapy resistance and tumor occurrence. CSCs specific therapy may achieve excellent therapeutic… Expand