Sanjiv Joshi

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OBJECTIVES The goal of this study was to assess the prognostic significance of midwall and infarct patterns of late gadolinium enhancement (LGE) in aortic stenosis. BACKGROUND Myocardial fibrosis occurs in aortic stenosis as part of the hypertrophic response. It can be detected by LGE, which is associated with an adverse prognosis in a range of other(More)
BACKGROUND Cardiovascular magnetic resonance (CMR) is the gold standard non-invasive method for determining left ventricular (LV) mass and volume but has not been used previously to characterise the LV remodeling response in aortic stenosis. We sought to investigate the degree and patterns of hypertrophy in aortic stenosis using CMR. METHODS Patients with(More)
A persistent left superior vena cava (LSVC) draining through a dilated coronary sinus into the right atrium is a relatively common congenital cardiovascular anomaly. It is readily identified by cardiovascular magnetic resonance (CMR). However, a LSVC draining into the left atrium (LA) and associated with unroofing of the coronary sinus, with resulting(More)
OBJECTIVES Risk assessment of patients with aortic stenosis (AS) undergoing aortic valve replacement (AVR) is challenging. We set out to determine the impact of myocardial late gadolinium enhancement (LGE), as detected by cardiovascular magnetic resonance (CMR), on postoperative outcomes following AVR. METHODS A prospective observational study was conducted(More)
A 34-year-old woman of Afro Caribbean origin presented to the HIV clinic with a few days’ history of chest pain, chills, and malaise. The chest pain was intermittent, severe, central, radiating to the left arm, worse on lying down, and better on sitting forward. This was preceded by an episode of collapse after palpitations a week earlier. On examination,(More)
Aortic stenosis (AS) is characterized by progressive narrowing of the valve and the hypertrophic response of the left ventricle (LV) that ensues (1). Although initially adaptive, the hypertrophic response ultimately decompensates and patients transition from hypertrophy to heart failure, symptom development, and adverse events. Pathology studies have(More)
Acute limb ischemia, a serious medical condition characterized by a rapid decrease in limb perfusion, often threatens limb viability. Acute limb ischemia can be secondary to multitude of causes, with the two most common being embolus and thrombosis in situ secondary to underlying peripheral artery disease. In this report we present an unusual case of acute(More)
Methods Consecutive patients with moderate or severe AS (aortic valve area <1.5cm), normal coronary arteries and no other significant valve lesion or cardiomyopathy were scanned by 1.5T magnetic resonance and compared with contemporary ageand sex-matched healthy, control subjects. The extent and patterns of hypertrophy were assessed from volumetric cine(More)
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