Sanjay P. Prabhu

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OBJECTIVE To compare the prevalence and type of early developmental lesions in patients with a clinical presentation consistent with electrical status epilepticus in sleep either with or without prominent sleep-potentiated epileptiform activity (PSPEA). METHODS We performed a case-control study and enrolled patients with 1) clinical features consistent(More)
This article describes some of the newer techniques that are being used in the clinical assessment of patients following mild to moderate TBI, addresses their use in the acute setting, and explores their potential role in long-term follow-up. Also addressed are the challenges faced before some of these newer techniques can be incorporated into routine(More)
To assess changes in apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values in brainstem gliomas (BSG) in children and to observe the temporal evolution of changes in the white matter tracts following therapy using diffusion tensor imaging (DTI) analysis. Serial ADC and FA measurements were obtained in three patients with newly diagnosed(More)
Imaging and delineation of the optic radiations (OpRs) remains challenging, despite repeated attempts to achieve reliable validated tractography of this complex structure. Previous studies have used varying methods to generate representations of the OpR which differ markedly from one another and, frequently, from the OpR's known structure. We systematically(More)
The fossa navicularis is a notch-like bone defect in the basiocciput that has been hitherto considered as an anatomical variant of the clivus and not previously described as a potential source of clival or skull base pathology. We report the imaging findings in a 5-year-old child who presented acutely with a retropharyngeal abscess and osteomyelitis of the(More)
There has been an increase in the use of digital imaging in recent years and radiologists have almost universally accepted the use of computers in their day-to-day work. Completely filmless radiology departments, with all reporting being done on visual display terminals and picture archiving and communications systems (PACS) around the department, are(More)
OBJECTIVE To utilize real-time electrical impedance tomography to guide lung protective ventilation in an animal model of acute respiratory distress syndrome. DESIGN Prospective animal study. SETTING Animal research center. SUBJECTS Twelve Yorkshire swine (15 kg). INTERVENTIONS Lung injury was induced with saline lavage and augmented using large(More)
White matter fiber bundles of the brain can be delineated by tractography utilizing multiple regions-of-interest (MROI) defined by anatomical landmarks. These MROI can be used to specify regions in which to seed, select, or reject tractography fibers. Manual identification of anatomical MROI enables the delineation of white matter fiber bundles, but(More)
PURPOSE Currently, in continuous spikes and waves during sleep (CSWS) there is a lack of systematic assessments of the clinically relevant stages and the evolution of the electroencephalographic features. The aim of this study is to describe the evolution over time of clinical and electroencephalographic features in CSWS. METHODS We enrolled patients from(More)
   In planning for a potentially curative resection of the epileptogenic zone in patients with pediatric epilepsy, invasive monitoring with intracranial EEG is often used to localize the seizure onset zone and eloquent cortex. A precise understanding of the location of subdural strip and grid electrodes on the brain surface, and of depth electrodes in the(More)