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Osmotic capsules: A universal oral, controlled-release drug delivery dosage form.
An osmotic, oral, controlled-release capsule is described. This capsule provides drug delivery at fixed delivery rates (T(80%)=6 or 14h) independent of drug properties (e.g., solubility) or drugExpand
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Magnetic resonance imaging and relaxometry to study water transport mechanisms in a commercially available gastrointestinal therapeutic system (GITS) tablet.
The hydration of 4 mg Cardura XL (Pfizer), a commercially available gastrointestinal therapeutic system (GITS) tablet, was investigated using magnetic resonance imaging (MRI). A short echo timeExpand
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Formulations d'enzalutamide
La presente invention concerne des formulations d'enzalutamide et leur utilisation pour traiter des troubles hyperproliferatifs.
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Médicament enduit par vaporisation et polymère multiparticulaires sur un noyau pouvant fondre
La presente invention concerne une composition pharmaceutique comprenant des elements multiparticulaires comprenant un noyau fondu-congele et une couche de dispersion amorphe solide d'un medicamentExpand
Small-Scale Manufacture of Modified-Release Coated Beads For Preclinical Drug Discovery Research
A small bead size (60 µm) was chosen to enable syringe delivery. A dense material (glass) was used to allow adequate fluidization in the micro-scale fluid-bed coater. CR coated beads were preparedExpand
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