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  • Sanghamitra Dey, James Matthew Doyle Lane, Richard E Lee, Eric J. Rubin, James C. Sacchettini
  • Chemistry, Medicine
  • Biochemistry
  • 2010 (First Published: 10 August 2010)
  • Mycobacterium tuberculosis (Mtb) depends on biotin synthesis for survival during infection. In the absence of biotin, disruption of the biotin biosynthesis pathway results in cell death rather thanContinue Reading
  • Sanghamitra Dey, Zhiqin Hu, Xiao Lan Xu, James C. Sacchettini, Gregory A Grant
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2005 (First Published: 15 April 2005)
  • D-3-Phosphoglycerate dehydrogenase (PGDH) from Mycobacterium tuberculosis has been isolated to homogeneity and displays an unusual relationship to the Escherichia coli and mammalian enzymes. InContinue Reading
  • Sanghamitra Dey, Gregory A Grant, James C. Sacchettini
  • Biology, Medicine, Materials Science
  • The Journal of biological chemistry
  • 2005 (First Published: 15 April 2005)
  • Phosphoglycerate dehydrogenases exist in at least three different structural motifs. The first D-3-phosphoglycerate dehydrogenase structure to be determined was from Escherichia coli and is aContinue Reading