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PURPOSE The effects of excess weight on the development of cancers are controversial, and little is known for populations outside the United States and Europe. We conducted this study to assess the effects of excess weight with a large cohort of Koreans. METHODS We assessed the relationship between body mass index (BMI) and various cancers in a 10-year(More)
BACKGROUND The metabolic syndrome is associated with a high risk of cardiovascular disease morbidity and mortality. Light and moderate alcohol consumption have been associated with reduced cardiovascular disease morbidity and mortality. OBJECTIVE This study was performed to examine the association between alcohol consumption and the metabolic syndrome. (More)
The effects of vegetable preference and leisure-time physical activity (LPA) on cancer have been inconsistent. We examined the effects of dietary preference and physical activity, as well as their combined effect on cancer risk. This prospective cohort study included 444,963 men, older than 40 years, who participated in a national health examination program(More)
OBJECTIVE The need for a lower BMI to classify overweight in Asian populations has been controversial. Using both disease and mortality outcomes, we investigated whether lower BMI cut-off points are appropriate for identifying increased health risk in Koreans. RESEARCH METHODS AND PROCEDURES We conducted a cohort study among 773,915 men and women from 30(More)
In Korea, a person with a body mass index (BMI) ≥25 kg/m(2) is considered obese, and a person with a BMI ≥30 kg/m(2) is classified as severely obese. Central obesity is defined as a waist circumference ≥90 cm for Korean men and ≥85 cm for Korean women. Recent epidemiologic data show that the prevalence of severe obesity and metabolic syndrome is steadily(More)
BACKGROUND AND AIM Elevated intraocular pressure (IOP), a well-known risk factor for glaucoma, has recently been shown to be associated with some metabolic complications and obesity. We investigated the link between IOP and metabolic disturbances, focusing especially on metabolic syndrome and insulin resistance. METHODS Eye examinations, including IOP(More)
INTRODUCTION The importance of managing the metabolic syndrome has been emphasized in the prevention of cardiovascular disease. Although South Koreans have a low prevalence of obesity, little information is available about the prevalence of the metabolic syndrome and its associated risk factors. METHODS Data was obtained from individuals aged 20-79 years(More)
The objective of this study was to examine the relationship between dairy product intake and the incidence of metabolic syndrome (MetS) and its components among middle-aged Koreans. We examined 7,240 adults aged 40-69 yr without MetS at baseline over a 45.5-month follow-up period. They were taken from the Anseong and Ansan cohort of the Korean Genome and(More)
Salt sensitivity is a risk factor for cardiovascular morbidity and mortality. To date, only a few genetic variations have been identified as being associated with salt sensitivity. This study aimed to estimate the prevalence of salt sensitivity in the Korean population and to identify genetic variants affecting its development. A total of 101 Korean(More)
M etabolic syndrome is highly prevalent in the U.S. (age-adjusted prevalence of 23.7%) (1) and in Korea (20.8% for men and 26.9% for women) (2). This syndrome is well documented to increase the risk for developing type 2 diabetes and cardiovascular diseases (CVDs) and is associated with an all-cause mortality (3–5). Physical inactivity, excessive weight(More)