Sang-Kyoon Hong

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In this paper, we propose an accurate and efficient method for approximate subsequence search in large DNA databases. The proposed method basically adopts a binary trie as its primary structure and stores all the window subsequences extracted from a DNA sequence. For approximate subsequence search, it traverses the binary trie in a breadth-first fashion and(More)
BACKGROUND PLA2G6-associated neurodegeneration (PLAN) encompasses infantile- or atypical neuroaxonal dystrophy, and adult-onset dystonia-parkinsonism. Examination of the intrafamilial phenotypic variability of PLAN by neuroimaging data and background genetic differences has not been reported. METHODS We report clinical, genetic (whole exome sequencing(More)
BACKGROUND Most studies of smartphone-based assessments of motor symptoms in Parkinson's disease (PD) focused on gait, tremor or speech. Studies evaluating bradykinesia using wearable sensors are limited by a small cohort size and study design. We developed an application named smartphone tapper (SmT) to determine its applicability for clinical purposes and(More)
We have recently proposed a rank-based approach as a new microarray data integration method. The rank-based approach, which converts the expression value of each sample into a rank value within the sample, enables us to directly integrate samples generated by different laboratories and microarray technologies. In this study, we show that a non-parametric(More)
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