Sang-Hyun Min

Bu Young Choi1
Do-Hee Kim1
1Bu Young Choi
1Do-Hee Kim
1Nayoung Kwon
1Kyung Oh Jung
1Hoang Kieu Chi Ngo
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There is growing interest in identifying regulators of autophagy. The molecular mechanism underlying transforming growth factor-β activated kinase 1 (TAK1)-induced autophagy is poorly understood. We found that TAK1 inhibits p70 S6 kinase1 (S6K1) phosphorylation by interfering interaction of raptor with S6K1, thus inducing autophagy. The factors that(More)
  • Hyeong-jun Han, Nayoung Kwon, Min-A Choi, Kyung Oh Jung, Juan-Yu Piao, Hoang Kieu Chi Ngo +9 others
  • 2016
Peptidyl prolyl isomerase (PIN1) regulates the functional activity of a subset of phosphoproteins through binding to phosphorylated Ser/Thr-Pro motifs and subsequently isomerization of the phosphorylated bonds. Interestingly, PIN1 is overexpressed in many types of malignancies including breast, prostate, lung and colon cancers. However, its oncogenic(More)
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