Sang-Hwan Kim

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BACKGROUND Recently, osteocalcin was found to regulate blood glucose, insulin secretion, and fat deposition in mice. However, the relationship between osteocalcin levels and factors related to glucose metabolism in humans has not yet been investigated. We investigated the relationship between osteocalcin and glucose metabolism in postmenopausal women. (More)
A novel β-glucosidase (BGL)-producing strain was isolated and identified as Penicillium purpurogenum KJS506 based on its morphology and internal transcribed spacer (ITS) rDNA gene sequence. When rice straw and corn steep powder were used as carbon and nitrogen sources, respectively, the maximal BGL activity of 12.3 U ml−1, one of the highest levels among(More)
BACKGROUND Studies on the effects of bilirubin on cardiovascular disease have typically focused only on total serum bilirubin composed with direct bilirubin plus indirect bilirubin. In this study, we examined which type of fasting bilirubin is more associated with the metabolic syndrome (MS). METHODS Five thousand six hundred and fifty-four individuals(More)
BACKGROUND Epidemiologic studies have shown that serum total bilirubin is inversely related to an increased risk of coronary artery disease. However, the number of studies which have focused on the relationship between bilirubin and C-reactive protein (CRP), which is a marker reflecting chronic vascular inflammation, are limited. METHOD This(More)
BACKGROUND Carcinoembryonic antigen (CEA), a serological marker of malignant tumors, demonstrates a modest increase under nonmalignant conditions and the pro-inflammatory features of CEA suggest that CEA may be related to insulin resistance and metabolic syndrome. METHODS A total of 7075 female Korean non-smokers who underwent health check-ups were(More)
BACKGROUND Nursing home-acquired pneumonia (NHAP) is the leading cause of death among long-term care residents. AIMS To compare current scoring indices (NHAP model score, Pneumonia Severity Index (PSI), CURB-65 (confusion, urea nitrogen, respiratory rate, blood pressure, age >65 years) and SOAR (systolic blood pressure, oxygenation, age, respiratory(More)
Adiponectin levels are significantly lower in obese adult patients with type 2 diabetes mellitus, essential hypertension, dyslipidemia, and cardiovascular disease. However, the role of hypoadiponectinemia in nonobese healthy adults has not been fully elucidated. In this study, we examined the association between hypoadiponectinemia and cardiovascular risk(More)
The enzyme 20α-hydroxysteroid dehydrogenase (20α-HSD) catalyzes the conversion of progesterone to its inactive form, 20α-hydroxyprogesterone. This enzyme plays a critical role in the regulation of luteal function in female mammals. In this study, we conducted the characterization and functional analyses of bovine 20α-HSD from placental and ovarian tissues.(More)
Although a variety of studies have reported the association between age related changes in muscle mass and the functional impairments of the elderly, few have reported on the modifiable lifestyle factors that are related to sarcopenia. Three thousand five hundred ninety-eight men in nationally representative cross-sectional, population-representative(More)
BACKGROUND This study compares biomarker (including procalcitonin, pro-ANP, and copeptin) levels to pneumonia severity scores to predict 30-day mortality in NHAP (nursing home acquired pneumonia) patients. METHODS Seventy three patients aged ≥ 65 y, admitted to general hospitals and who fulfilled the definition of NHAP were included in the study. Data(More)