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  • Keon Wook Kang, Seung Jin Lee, Jeong Weon Park, Sang Geon Kim
  • Biology, Medicine
  • Molecular pharmacology
  • 2002 (First Published: 1 November 2002)
  • Expression of phase II detoxifying genes is regulated by NF-E2-related factor 2 (Nrf2)-mediated antioxidant response element (ARE) activation. We showed previously that phosphatidylinositol 3Continue Reading
  • Yeonkyung Kim, Rui Zhao, +5 authors Sung Chan Kim
  • Chemistry, Medicine
  • British journal of pharmacology
  • 2008 (First Published: 1 May 2008)
  • BACKGROUND AND PURPOSE Glycyrrhizae radix has been widely used as a cytoprotective, plant-derived medicine. We have identified a flavanoid, liquiritigenin, as an active component in extracts ofContinue Reading
  • Ae Kyung Lee, Sang Hyun Sung, Young Choong Kim, Sang Geon Kim
  • Chemistry
  • 2003 (First Published: 1 May 2003)
  • Sauchinone, a lignan isolated from Saururus chinensis (Saururaceae), is a diastereomeric lignan with cytoprotective and antioxidant activities in cultured hepatocytes. The effects of sauchinone onContinue Reading
  • Seong Hwan Hwahng, Sung Hwan Ki, Eun Ju Bae, Hyun Eun Kim, Sang Geon Kim
  • Biology, Medicine
  • Hepatology
  • 2009 (First Published: 1 June 2009)
  • UNLABELLED Dithiolethiones, a novel class of adenosine monophosphate-activated protein kinase (AMPK) activators, prevent insulin resistance through AMPK-dependent p70 ribosomal S6 kinase-1 (S6K1)Continue Reading
  • Eun Young Park, Il Je Cho, Sang Geon Kim
  • Biology, Medicine
  • Cancer research
  • 2004 (First Published: 15 May 2004)
  • Cancer chemopreventive agents transcriptionally induce glutathione S-transferase (GST), which can protect cells from chemical-induced carcinogenesis. Activation of either NF-E2-related factor-2Continue Reading
  • K W Kang, Jong Hoon Ryu, Sang Geon Kim
  • Biology, Medicine
  • Molecular pharmacology
  • 2000 (First Published: 1 November 2000)
  • The protective adaptive response to electrophiles and reactive oxygen species is mediated by the enhanced expression of the phase II detoxifying genes through antioxidant response elements (AREs).Continue Reading