Sang Eun Park

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BACKGROUND Quantifying the in vivo cartilage contact mechanics of the knee may improve our understanding of the mechanisms of joint degeneration and may therefore improve the surgical repair of the joint after injury. OBJECTIVE To measure tibiofemoral articular cartilage contact kinematics during in vivo knee flexion. STUDY DESIGN Descriptive laboratory(More)
Although a recent study (Zhang et al. Cell Death Differ 2002; 9; 790-800) presented that acetylcholinesterase (AChE) might be an important common component in leading to various types of apoptosis, the molecular mechanism, by which AChE functions, had remained elusive before that study. We explored the role of AChE in apoptosis by silencing the AChE gene.(More)
BACKGROUND The anterior cruciate ligament (ACL) constrains the anterior translation and axial rotation of the tibia. However, the effect of ACL injury on the mediolateral translation and varus-valgus rotation of the tibia is unknown. Because of the oblique orientation of the ACL, we hypothesized that ACL deficiency alters mediolateral translation and(More)
The biomechanical literature over the past three decades reports direct measurements of human hip joint contact forces from instrumented implants which in general are quite different than estimates of contact forces based on external kinematic-ground reaction force data and inverse Newtonian analyses. Because direct physical measurement establishes(More)
Even though posterior substituting total knee arthroplasty has been widely used in surgery, how the cam-post mechanism (posterior substituting mechanism) affects knee joint kinematics and function in patients is not known. The objective of the present study was to investigate posterior femoral translation, internal tibial rotation, tibiofemoral contact, and(More)
The collateral ligaments of the knee are important in maintaining knee stability. However, little data has been reported on the in vivo function of the collateral ligaments. The objective of this study was to investigate the change in length of different fiber bundles of the medial collateral ligament (MCL), deep fibers of the MCL (DMCL) and the lateral(More)
We carried out an anthropometric analysis using three dimensional computer tomographic measurements of the cut surface of the proximal tibia in 200 knees that were obtained from 50 male and 50 female Korean cadavers. We measured the mediolateral (ML), middle anteroposterior (AP), medial and lateral anteroposterior dimensions and the aspect ratio (ML/AP) of(More)
Altered patellofemoral joint contact pressures are thought to contribute to patellofemoral joint symptoms. However, little is known about the relationship between tibiofemoral joint kinematics and patellofemoral joint contact pressures. The objective of this paper was to investigate the effect of tibiofemoral joint kinematics on patellofemoral joint(More)
Unicondylar knee arthroplasty (UKA) has gained popularity in the recent years for treating medial compartment osteoarthritis of the knee joint in the Asian population. There is little information about the anthropometry of the resected bony surfaces of the knee joint in these population groups for designing the appropriate size-matched UKA components. We(More)
Keloids are pathologic proliferations of the dermal layer of the skin resulting from excessive collagen production and deposition. Hepatocyte growth factor (HGF) increases the expression of matrix metalloproteinase (MMP)-1 and suppresses collagen synthesis to modulate extracellular matrix turnover. To investigate the anti-fibrotic effects of HGF, we examine(More)