Learn More
An emerging demand for the precise manipulation of cells and particles for applications in cell biology and analytical chemistry has driven rapid development of ultrasonic manipulation technology. Compared to the other manipulation technologies, such as magnetic tweezing, dielectrophoresis and optical tweezing, ultrasonic manipulation has shown potential in(More)
Piezocrystals, especially the relaxor-based ferroelectric crystals, have been subject to intense investigation and development within the past three decades, motivated by the performance advantages offered by their ultrahigh piezoelectric coefficients and higher electromechanical coupling coefficients than piezoceramics. Structural anisotropy of(More)
Many applications of ultrasound for sensing, actuation and imaging require miniaturized and low power transducers and transducer arrays integrated with electronic systems. Piezoelectric micromachined ultrasound transducers (PMUTs), diaphragm-like thin film flexural transducers typically formed on silicon substrates, are a potential solution for integrated(More)
Physics in therapy is as diverse as it is substantial. In this review, we highlight the role of physics--occasionally transitioning into engineering--through discussion of several established and emerging treatments. We specifically address minimal access surgery, ultrasound, photonics, and interventional MRI, identifying areas in which complementarity is(More)
Ultrasonic C-scanning is widely used for large area flaw detection but acquiring the full RF waveform for each surface point – Full Waveform Capture (FWC)-offers many advantages. A system that used phased arrays to achieve this without loss of area coverage rate has been reported [1]. FWC allows many signal processing operations, previously only possible at(More)
BACKGROUND Image-guided surgery has become standard practice during surgical resection, using preoperative magnetic resonance imaging. Intraoperative ultrasound (IoUS) has attracted interest because of its perceived safety, portability, and real-time imaging. This report is a meta-analysis of intraoperative ultrasound in gliomas. METHODS Critical(More)
Relaxor-based piezoelectric single crystals have experienced three generations of development, from binary (e.g. PMN-PT) through ternary (e.g. PIN-PMN-PT) to doped ternary (e.g. Mn:PIN-PMN-PT). With improved composition and other relevant factors, these materials exhibit an extraordinary degree of piezoelectricity and ultrahigh electromechanical coupling(More)
Background/introduction NANOPORATION project sets out to explore specific solutions to overcome the current challenges of targeted drug delivery (TDD) to tumours using magnetic resonance imaging guided focused ultrasound (MRgFUS) to cavitate microbubbles (MBs) for increasing cell perme-ability and to open 'drug nano-capsules' for releasing proven active(More)
Around 52,000 people are diagnosed with breast cancer each year in the UK. With the controversy around over diagnosis arising from the breast screening programme there is intense interest in the possibility of safe effective non-invasive treatment of cancers. As a non-invasive method of lumpectomy, focused ultrasound surgery (FUS) may offers reduced risk of(More)