Sandrine A Zweifel

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OBJECTIVE To describe tubular structures found in the outer retina seen in a variety of retinal disorders. METHODS Sixty-nine eyes of 63 patients were examined with spectral-domain optical coherence tomography. Optical coherence tomography C-scans were correlated with their corresponding B-scans. The prevalence, number, size, and shape of the tubular(More)
PURPOSE To characterize reticular pseudodrusen, a potential risk factor for late age-related macular degeneration. DESIGN Retrospective, observational case series. PARTICIPANTS Fifty-eight eyes of 33 patients with pseudodrusen (20 female). METHODS Consecutive patients with reticular pseudodrusen, diagnosed by their typical appearance and distribution(More)
PURPOSE To determine the prevalence and significance of subretinal drusenoid deposits (reticular pseudodrusen) among patients with age-related macular degeneration (AMD). DESIGN A prospective study with a nested case-control study of consecutive patients with AMD seen in a referral retinal practice. PARTICIPANTS There were 153 patients with AMD, 131 of(More)
PURPOSE To examine the posterior anatomic structure of eyes with dome-shaped macula using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). DESIGN Retrospective observational case series. METHODS Patients with dome-shaped macula, a condition defined as convex elevation of the macula as compared with the surrounding(More)
PURPOSE To investigate spectral domain optical coherence tomography and autofluorescence findings in eyes with pseudoxanthoma elasticum. METHODS A retrospective analysis of visual acuity, spectral domain optical coherence tomography, and autofluorescence findings of consecutive patients with pseudoxanthoma elasticum was performed. The spectral domain(More)
PURPOSE To correlate clinical observations with multimodal imaging analysis in acquired vitelliform lesions (AVLs) and to elucidate their nature, pathogenesis, and natural course. METHODS Clinical examination, color fundus photography, fluorescein angiography, near-infrared reflectance, fundus autofluorescence, and spectral-domain optical coherence(More)
PURPOSE The purpose of this study was to analyze long-term outcomes for the treatment of type 3 neovascularization/retinal angiomatous proliferation using a "Treat and Extend" dosing regimen for antivascular endothelial growth factor therapy. METHODS This was a retrospective analysis of visual acuity and optical coherence tomography data of 11 eyes of 10(More) Updated information and services can be found at: These include: References This article cites 15 articles, 6 of which can be accessed free at: service Email alerting box at the top right corner of the online article. Receive free email alerts when new(More)
PURPOSE The purpose of the study was to analyze long-term outcomes for the treatment of type 1 (subretinal pigment epithelium) neovascularization using a modified "treat and extend" antivascular endothelial growth factor dosing regimen. METHODS We performed a retrospective, noncomparative analysis of visual acuity, funduscopic, and optical coherence(More)