Sandra Nassa Sampietre

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BACKGROUND Ischemia and reperfusion (I/R) causes tissue damage and intracellular calcium levels are a factor of cell death. Sodium calcium exchanger (NCX) regulates calcium extrusion and Trisulfated Disaccharide (TD) acts on NCX decreasing intracellular calcium through the inhibition of the exchange inhibitory peptide (XIP). OBJECTIVES The aims of this(More)
CONTEXT Some authors have found beneficial effect of statins in certain inflammatory conditions, but the effect of statins on acute pancreatitis is not yet defined. OBJECTIVE The aim of this study was to evaluate the effect of simvastatin on an experimental model of mild and severe acute pancreatitis. ANIMALS One hundred and one Wistar rats with(More)
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