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The algorithm proposed in this paper allows to automatically segment the optic disc from a fundus image. The goal is to facilitate the early detection of certain pathologies and to fully automate the process so as to avoid specialist intervention. The method proposed for the extraction of the optic disc contour is mainly based on mathematical morphology(More)
The potential of aerosol phage therapy for treating lung infections has been demonstrated in animal models and clinical studies. This work compared the performance of two dry powder formation techniques, spray freeze drying (SFD) and spray drying (SD), in producing inhalable phage powders. A Pseudomonas podoviridae phage, PEV2, was incorporated into(More)
The algorithm proposed in this paper allows to segment the optic disc from a fundus image. The goal is to facilitate the early detection of certain pathologies and to fully automate the process so as to avoid specialist intervention. The method used for the extraction of the optic disc contour is based on a variant of the watershed transformation, the(More)
The analysis of retinal blood vessels provides useful information for medical diagnosis of several diseases such as cardiovascular risk or diabetic and hypertensive retinopathy. These diseases affect retinal vessels so that an abnormal calibre of veins or arteries could indicate the presence of some of them. So, before analysing vessel calibres, it is(More)
As Computer-Assisted Language Learning (CALL) has taken an important role in foreign language teaching and learning, not only is concrete data about the usefulness of technology-mediated environments for these purposes necessary, but also how the learning process is improved in such environments when learner training for CALL. The objective of this paper is(More)
The goal of the software proposed in this paper is to assist ophthalmologists in diagnosis and disease prevention, helping them to determine cardiovascular risk or other diseases where the vessels can be altered, as well as to monitor the pathology progression and response to different treatments. The performance of the tool has been evaluated by means of a(More)
This paper describes a new approach to determine vascular skeleton in retinal images. This approach is based on mathematical morphology along with curvature evaluation. In particular, a variant of the watershed transformation, the stochastic watershed, is applied to extract the vessel center-line. Its goal is to obtain directly the skeleton of the retinal(More)
BACKGROUND AND OBJECTIVE This paper presents BRAIM, a computer-aided diagnosis (CAD) system to help clinicians in diagnosing and treatment monitoring of brain diseases from magnetic resonance image processing. BRAIM can be used for early diagnosis of neurodegenerative diseases such as Parkinson, Alzheimer or Multiple Sclerosis and also for brain lesion(More)
This paper investigates discrimination capabilities in the texture of fundus images to differentiate between pathological and healthy images. For this purpose, the performance of local binary patterns (LBP) as a texture descriptor for retinal images has been explored and compared with other descriptors such as LBP filtering and local phase quantization. The(More)