Sandra Luz Gastélum Ramírez

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Using adult male C57BL/6 mice that express a yellow fluorescent protein transgene in their motor neurons, we induced experimental autoimmune encephalomyelitis (EAE) by immunization with myelin oligodendrocyte glycoprotein peptide 35-55 (MOG peptide) in complete Freund's adjuvant (CFA). Control mice of the same transgenic strain received CFA without MOG(More)
Stress-induced hormones can alter the inflammatory response to tissue injury; however, the precise mechanism by which epinephrine influences inflammatory response and wound healing is not well defined. Here we demonstrate that epinephrine alters the neutrophil (polymorphonuclear leukocyte (PMN))-dependent inflammatory response to a cutaneous wound. Using(More)
Knowledge Management (KM) is considered as a tool for improving control over knowledge in the organizations, supporting their processes and functions. Knowledge, explicit and tacit, is distributed in the organization, for exploding it and really generates a competitiveness oriented value. It is necessary to design KM strategies and implement Knowledge(More)
Memories are difficult to pin down, in part because there is no single kind—they can be fragmentary or interwoven, stable or ephemeral, easily recalled or long dormant. Exploring how learning and memory are encoded by changes in neuronal structure is a pursuit that supplants the abstract with something tangible, a toehold for understanding one of the most(More)
OBJECTIVE To describe the unique phenotype and genetic findings in a 57-year-old female with a rare form of congenital myasthenic syndrome (CMS) associated with longstanding muscle fatigability, and to investigate the underlying pathophysiology. METHODS We used whole-cell voltage clamping to compare the biophysical parameters of wild-type and(More)
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