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  • Paulus Kirchhof, Peter C. Kahr, +10 authors Nigel Brown
  • Biology, Medicine
  • Circulation. Cardiovascular genetics
  • 2011 (First Published: 1 April 2011)
  • BACKGROUND Intergenic variations on chromosome 4q25, close to the PITX2 transcription factor gene, are associated with atrial fibrillation (AF). We therefore tested whether adult hearts express PITX2Continue Reading
  • Paulus Kirchhof, Eloi Marijon, +21 authors Frank Ulrich Müller
  • Medicine
  • International journal of cardiology
  • 2013 (First Published: 1 June 2013)
  • BACKGROUND AND METHODS Atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical practice. The substrate of AF is composed of a complex interplay between structural and functionalContinue Reading
  • Christoph Waldeyer, Larissa Fabritz, +8 authors Paulus Kirchhof
  • Medicine
  • Basic Research in Cardiology
  • 2009 (First Published: 1 September 2009)
  • Although numerous studies have reported the effects of genetic alterations on murine electrophysiology, the range of normal values for ventricular activation, repolarization, and arrhythmias in mouseContinue Reading
  • Larissa Fabritz, Mark G. Hoogendijk, +17 authors Paulus Kirchhof
  • Medicine
  • Journal of the American College of Cardiology
  • 2011 (First Published: 1 February 2011)
  • OBJECTIVES We used a murine model of arrhythmogenic right ventricular cardiomyopathy (ARVC) to test whether reducing ventricular load prevents or slows development of this cardiomyopathy. Continue Reading
  • Sandra Laakmann, Lisa Fortmüller, +5 authors Larissa Fabritz
  • Biology, Medicine
  • Naunyn-Schmiedeberg's Archives of Pharmacology
  • 2012 (First Published: 1 March 2013)
  • Organ-directed gene transfer remains an attractive method for both gaining a better understanding of heart disease and for cardiac therapy. However, virally mediated transfer of gene products intoContinue Reading
  • Paulus Kirchhof, Eloi Marijon, +21 authors Frank Ulrich Müller
  • Medicine
  • 2014 (First Published: 1 April 2014)
  • a Department of Cardiology and Angiology, University Hospital Munster, Germany b German Atrial Fibrillation Competence NETwork (AFNET), Germany c IZKF Munster, Germany (CarTel), Germany d INSERM,Continue Reading