Sandra Dias de Souza

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FGF21 is a novel secreted protein with robust anti-diabetic, anti-obesity, and anti-atherogenic activities in preclinical species. In the current study, we investigated the signal transduction pathways downstream of FGF21 following acute administration of the growth factor to mice. Focusing on adipose tissues, we identified FGF21-mediated downstream(More)
Site-directed mutagenesis was used to replace asparagine (Asn) residues with glutamine (Gln) at the five potential N-linked glycosylation sites located at positions 28, 97, 138, 143, and 182 in the extracellular domain of the porcine growth hormone receptor (pGHR). These mutated pGHR cDNAs were stably expressed in mouse L cells. Single substitution of the(More)
The increased performance of personal computers and their reduced cost has made it possible for development of PC based signal processing systems.Hospitals need several measurement systems that can measure physiological parameters of the patients. Although diagnostic medical instruments have been widely used, combining virtual instrument technology to(More)
Authors' contribution: BSZ was responsible for study design, overall direction of the steps, and preparation of the manuscript; SDS was responsible for collecting and analyzing data; HM was responsible for collecting and analyzing data; HAGT was responsible for reviewing the article and final draft; PBNL was responsible for reviewing the article. ABSTRACT(More)
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