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This study examined the faecal flora on days 4, 14, and 28 of 17 breast fed babies and 26 bottle fed babies receiving a modern infant formula based on demineralized whey. Generally among breast fed babies bifidobacteria and staphylococci were the predominant organisms, whereas in the formula fed babies the predominant organisms were enterococci, coliforms,(More)
The faecal flora of breast fed babies differs from that of bottle fed babies. We have shown that the use of a whey predominant formula rather than a casein predominant one induced a faecal flora generally closer to that of breast fed babies but substantial differences remained. The whey proteins of breast milk include much more lactoferrin than is found in(More)
Breast milk contains nucleotide salts that are only present in minimal amounts in modern infant formulas prepared from cows' milk. Nucleotides have been suggested as cofactors for the growth of bifidobacteria in vitro. Bifidobacteria are found to be more numerous in the faeces of breast fed babies compared with those of formula fed babies. Faecal flora were(More)
The intestinal flora of breast-fed infants differs from that of formula-fed infants. It is thought that this difference in flora may be one important reason why breast-fed babies suffer less from gastrointestinal disease. Differences in intestinal flora are reflected in the profile of faecal short chain fatty acids (SCFA). Very little is known about faecal(More)
Results from experiments in this laboratory using 59Fe suggest that bovine lactoferrin (Lf) has no effect on iron absorption in rats. A study was therefore carried out in newborn infants to measure the effects of Lf on iron retention. Bovine Lf was labeled with the stable isotope 58Fe and fed to 7-day-old infants in a standard milk formula. Iron retention(More)
We have measured by reversed-phase HPLC concentrations of amino acids in plasma in groups of 80 normal appropriate-weight term babies fed from birth either a casein formula (WhiteCap SMA, n = 26), a whey formula (Gold Cap SMA, n = 26), or breast milk (n = 28). They were studied from day 11 to week 15 postpartum. The trend was towards an increase in amino(More)
H uman milk banks provide an alternative to formula feeds for preterm babies when the mother's breast milk is unavailable. The first human milk bank in the United Kingdom opened at Queen Charlotte's Hospital, London in 1939. The emergence of the human immunodeficiency virus resulted in the disappearance of many human milk banks in the 1980s. However, there(More)
The faecal flora of a baby receiving a modern infant formula is substantially different from that of a breast fed baby. This difference is a little less when whey based formulas are used. The addition of bovine lactoferrin has no effect and there is some evidence that the presence of added iron in a formula moved the faecal flora further away from that of a(More)
Despite the extensive modifications of cows' milk to make an infant formula resemble human breast milk, we showed in a previous study that the faecal flora of breast fed babies still differs substantially from that of formula fed babies. This paper describes the effects that differences in the distribution of whey proteins and caseins exert on the faecal(More)
The fecal flora of a breast-fed baby is very different from that of a bottle-fed baby. This paper reviews five previous studies, performed at this hospital concerning the effect of various dietary components (whey proteins, casein, lactoferrin, iron, nucleotides) on the fecal flora. The babies received either breast milk or one of the test formulas from(More)