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The eukaryotic cell division cycle is coordinated by cyclin-dependent kinases (CDKs), represented by a single major serine/threonine kinase in yeasts (Cdc2/CDC28) and a family of kinases (CDK1 to CDK8) in human cells. Previously, two cdc2 homologs, cdc2MsA and cdc2MsB, have been identified in alfalfa (Medicago sativa). By isolating cDNAs using a cdc2MsA(More)
Nerve growth factor (NGF)-specific signal transduction leads to changes in protein methylation during neuronal differentiation of PC12 cells (Cimato et al. [1997] J. Cell Biol. 138:1089-1103). In the present work, we demonstrate that, among NGF-regulated proteins, arginine methylation is more prevalent than carboxylmethylation. Type I protein arginine(More)
Long-standing evidence indicates that human immunodeficiency virus type 1 (HIV-1) preferentially integrates into a subset of transcriptionally active genes of the host cell genome. However, the reason why the virus selects only certain genes among all transcriptionally active regions in a target cell remains largely unknown. Here we show that HIV-1(More)
This report describes an approach for the study of the biology of methylarginine proteins based on the generation of immunological reagents capable of recognizing the methylarginine status of cellular proteins. Two forms of an immunizing peptide were prepared based upon an amino acid sequence motif found most prevalently among verified(More)
ABSTRACT The currently hyped expectation of personalized medicine is often associated with just achieving the information technology led integration of biomolecular sequencing, expression and histopathological bioimaging data with clinical records at the individual patients' level as if the significant biomedical conclusions would be its more or less(More)
The chronic tissue damage associated with long-term diabetes mellitus may arise in part from in situ immune complex formation by accumulated immunoglobulins and/or antigens bound to long-lived structural proteins that have undergone excessive nonenzymatic glycosylation. In this report, we have tested this hypothesis using nonenzymatically glycosylated(More)
The entire genomic DNA sequence of the Gram-positive bacterium Bacillus subtilis reported in the SubtiList database has been subjected in this work to a complete bioinformatic analysis of the potential formation of secondary DNA structures such as hairpins and bending. The most significant of these structures have been mapped with respect to their genomic(More)
  • Ádám Balogh, Konferencia Tamás, G Fodor, A T Balogh, G Hosszu, F Kovacs +13 others
  • 2013
Screening for congenital heart diseases by murmurs using telemedical phonocardiography ". Endrédy István Endrédy István, Novák Attila: Egy hatékonyabb webes sablonszűrő algoritmus – avagy miként lehet a cumisüveg potenciális veszélyforrás Obamára nézve. Cím: Biomimetic model of the outer plexiform layer by incorporating memristive devices
This peer-reviewed article was published immediately upon acceptance. It can be downloaded, printed and distributed freely for any purposes (see copyright notice below). which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background
  • Janos V1urvai, Csaba Szepesvari, Csamid Bachrati, Sandor Pongor
  • 2007
We propose a neural net solution for the recognition of the do m ain-types or pmLein s, which is H. IlH.f'd and irnporLanL problem in hiol­ og)'. WI:' 1m'll:' rOlJnd thaL w;ing a clever· pf'f'pron�ssif 1 g ('edHliqIJp. r'elaLively HTlall nCII ral ncLwork..; perrorrn HII rpT·iscflgl.y well. Thc perrorrrmTices or the neural nets were measured by(More)
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