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A series of benzo[b][1, 8]naphthyridines has been synthesized by Friedländer condensation of 2-aminoquinoline-3-carbaldehyde 1 (o-aminoaldehyde) with active methylenes in basic medium. The fluorescence spectroscopic properties of some representative compounds has been studied in different organic solvents; moreover interaction with bovine serum albumin… (More)
Novel pyrazolo-pyrrolo-pyrimidine (PPP) derivatives having remarkable photophysical properties are designed with the help of theoretical semiempirical calculations. These compounds then synthesized successfully and studied effect of substituents on its photophysical properties.
A 17-year-old patient had a traumatic extrusion of 10 cm distal radial segment. The segment of bone was replaced after cleaning and autoclaving. At four years follow-up, there was complete incorporation with almost full functional recovery. We report this case for its rarity and successful result.
A rapid and efficient method for the synthesis of various poly-substituted benzo[b][1,8]naphthyridines in high yield has been developed via the Friedländer condensation of 2-aminoquinoline-3-carbaldehyde 1 with various alicyclic ketones in a base catalyst (aq. potassium hydroxide). A series of benzo[b][1,8]naphthyridines branched with various side-chains… (More)
An investigation was carried out by conducting a field experiment at the farm of the Mahatma Phule Krishi Vidyapeeth (MPKV), Rahuri. The significant grain yield of soybean (37.5 q ha−1) and maize (49 q ha−1) were observed in the treatment receiving 100 % recommended doses of Nitrogen, Phosphorus and Potassium (NPK) + in situ compost of crop residues,… (More)
The blue light-emitting pyrazolo[3,4-h][1,6]naphthyridines has been synthesized by Friedländer condensation of 4-amino-3-(4-phenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde (o-aminoaldehyde) 1 with different cyclic ketones and 1,3-diketones. The synthesized angular polycyclic naphthyridine derivatives were studied for Semi-empirical, thermal,… (More)
A series of benzo[b][1,8]naphthyridines has been synthesized by Friedländer condensation of 2-aminoquinoline-3-carbaldehyde 1 (o-aminoaldehyde) with alicyclic ketones in basic medium. Benzonaphthyridines branched with various side-chains and substituents are prepared with the aim of being investigated as a good fluorescent material. Electronic absorption… (More)
Heterocyclic orthoaminoaldehyde such as 4-amino-3-(4-phenyl)-1-phenyl-1H-Pyrazolo[3,4-b]pyridine-5-carbaldehyde was synthesized by multistep reactions involving reduction of azido derivative 2 with LAH to yield aminoalcohol 3 and oxidation of it with MnO(2) to aminoaldehyde 4.The pyridine ring annulated on to 4 by Friedländer condensation using… (More)