Sanaa A. Ahmed

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In May of 2011, an enteroaggregative Escherichia coli O104:H4 strain that had acquired a Shiga toxin 2-converting phage caused a large outbreak of bloody diarrhea in Europe which was notable for its high prevalence of hemolytic uremic syndrome cases. Several studies have described the genomic inventory and phylogenies of strains associated with the outbreak(More)
Microbial hydrolysis of polysaccharides is critical to ecosystem functioning and is of great interest in diverse biotechnological applications, such as biofuel production and bioremediation. Here we demonstrate the use of a new, efficient approach to recover genomes of active polysaccharide degraders from natural, complex microbial assemblages, using a(More)
Although serotype O157:H7 is the predominant enterohemorrhagic Escherichia coli (EHEC), outbreaks of non-O157 EHEC that cause severe foodborne illness, including hemolytic uremic syndrome have increased worldwide. In fact, non-O157 serotypes are now estimated to cause over half of all the Shiga toxin-producing Escherichia coli (STEC) cases, and outbreaks of(More)
Endocytosis and vesicle trafficking are required for optimal neural transmission. Yet, little is currently known about the evolution of neuronal proteins regulating these processes. Here, we report the first phylogenetic study of NEEP21, calcyon, and P19, a family of neuronal proteins implicated in synaptic receptor endocytosis and recycling, as well as in(More)
Escherichia coli O145:H28 strain RM12581 was isolated from bagged romaine lettuce during a 2010 U.S. lettuce-associated outbreak. E. coli O145:H28 strain RM12761 was isolated from ice cream during a 2007 ice cream-associated outbreak in Belgium. Here we report the complete genome sequences and annotation of both strains.
Continued advancements in sequencing technologies have fueled the development of new sequencing applications and promise to flood current databases with raw data. A number of factors prevent the seamless and easy use of these data, including the breadth of project goals, the wide array of tools that individually perform fractions of any given analysis, the(More)
1 From raw reads to trees: Whole genome SNP phylogenetics across the tree of 1 life 2 3 Sanaa A. Ahmed, Chien-Chi Lo, Po-E Li, Karen W. Davenport, and Patrick S. G. Chain 4 5 Biome Sciences, Bioscience Division, Los Alamos National Laboratory, MS-M888, Los 6 Alamos, NM 87545 7 Corresponding author: 8 Patrick S.G. Chain 9 Scientist IV 10 Los Alamos National(More)
1 From raw reads to trees: Whole genome SNP phylogenetics across the tree of 1 life 2 3 Sanaa A. Ahmed, Chien-Chi Lo, Po-E Li, Karen W. Davenport, and Patrick S. G. Chain 4 5 Biome Sciences, Bioscience Division, Los Alamos National Laboratory, MS-M888, Los 6 Alamos, NM 87545 7 Corresponding author: 8 Patrick S.G. Chain 9 Scientist IV 10 Los Alamos National(More)
Introduction: Smoking can affect hormone secretion; some of these effects are associated with important clinical implications. These effects are mainly mediated by the action of nicotine. Curcumin is a well known antioxidant agent. Aim of the work: To study the protective role of curcumin against nicotine induced toxic effects on the adrenal medulla.(More)
We report here the genome sequence of Thauera sp. strain SWB20, isolated from a Singaporean wastewater treatment facility using gel microdroplets (GMDs) and single-cell genomics (SCG). This approach provided a single clonal microcolony that was sufficient to obtain a 4.9-Mbp genome assembly of an ecologically relevant Thauera species.
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