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The compositions of lesion types that precede and that may initiate the development of advanced atherosclerotic lesions are described and the possible mechanisms of their development are reviewed. While advanced lesions involve disorganization of the intima and deformity of the artery, such changes are absent or minimal in their precursors. Advanced lesions(More)
IMPORTANCE Cigarette smoking increases the risk of surgery in Crohn's disease. However, the effect of smoking on the need for surgery for diverticulitis is unknown. OBJECTIVE We evaluated whether smoking was a risk factor for surgery among patients admitted to hospital with acute diverticulitis. DESIGN We conducted a population-based comparative cohort(More)
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