Samuel McCarthy

Publications15
h-index8
Citations192
Highly Influential Citations21
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Metal resistance and lithoautotrophy in the extreme thermoacidophile Metallosphaera sedula.
Archaea such as Metallosphaera sedula are thermophilic lithoautotrophs that occupy unusually acidic and metal-rich environments. These traits are thought to underlie their industrial importance for… Expand
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Role of an archaeal PitA transporter in the copper and arsenic resistance of Metallosphaera sedula, an extreme thermoacidophile.
Thermoacidophilic archaea, such as Metallosphaera sedula, are lithoautotrophs that occupy metal-rich environments. In previous studies, an M. sedula mutant lacking the primary copper efflux… Expand
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Contracting for Road and Highway Maintenance
The condition of the roads and highways in the United States is less than stellar. In order to help the government get more for its money, highway maintenance and construction are often contracted… Expand
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Expanding the Limits of Thermoacidophily in the Archaeon Sulfolobus solfataricus by Adaptive Evolution
ABSTRACT Extremely thermoacidophilic Crenarchaeota belonging to the order Sulfolobales flourish in hot acidic habitats that are strongly oxidizing. The pH extremes of these habitats, however, often… Expand
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Evolution of copper arsenate resistance for enhanced enargite bioleaching using the extreme thermoacidophile Metallosphaera sedula
Adaptive laboratory evolution (ALE) was employed to isolate arsenate and copper cross-resistant strains, from the copper-resistant M. sedula CuR1. The evolved strains, M. sedula ARS50-1 and M. sedula… Expand
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Increased acid resistance of the archaeon, Metallosphaera sedula by adaptive laboratory evolution
Extremely thermoacidophilic members of the Archaea such as the lithoautotroph, Metallosphaera sedula, are among the most acid resistant forms of life and are of great relevance in bioleaching. Here,… Expand
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Lawrence Berkeley National Laboratory Recent Work Title Expanding the Limits of Thermoacidophily in the Archaeon Sulfolobus solfataricus by Adaptive Evolution Permalink
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Nonmutational mechanism of inheritance in the Archaeon Sulfolobus solfataricus
Significance Archaea have considerable importance in ecology and evolution and have emerging roles in health. However, many of their cellular processes are under active study. Archaea are thought to… Expand
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Experimental Microbial Evolution of Extremophiles
Experimental microbial evolution (EME) and its variant, adaptive laboratory evolution (ALE), are emerging empirical strategies for understanding fundamental biological processes in microbes.… Expand
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Complete Genome Sequence of Sulfolobus solfataricus Strain 98/2 and Evolved Derivatives
ABSTRACT Sulfolobus solfataricus is a thermoacidophilic crenarcheote with a 3.0-Mb genome. Here, we report the genome sequence of S. solfataricus strain 98/2, along with several evolved derivatives… Expand
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