Samuel Galice

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AIMS Loss-of-function mutations in the cytoskeletal protein ankyrin-B (AnkB) cause ventricular tachyarrhythmias in humans. Previously, we found that a larger fraction of the sarcoplasmic reticulum (SR) Ca(2+) leak occurs through Ca(2+) sparks in AnkB-deficient (AnkB(+/-)) mice, which may contribute to arrhythmogenicity via Ca(2+) waves. Here, we(More)
In the context of ambient networks, this article describes a cryptographic protocol called Common History Extraction (CHE) protocol implementing a trust management framework. All the nodes are supposed to share the same cryptographic algorithms and protocols. An entity called imprinting station provides them with two pairs of public/private keys derived(More)
In the context of ambient networks where each small device must trust its neighborhood rather than a fixed network, we propose in this paper a \textit{trust management framework} inspired by known social patterns and based on the following statements: each mobile constructs itself a local level of trust what means that it does not accept recommendation by(More)
In the context of ambient networks where each small device must trust its neighborhood rather than a fixed network, we propose in this paper a trust management framework based upon social patterns. As in human interaction model, our proposal builds trust using history elements of past interactions with a local reputation model. The main features of our(More)
The OSGi platform is designed to make Java software extensible at runtime. This undeniably presents a great interest in several domains like embedded platforms or enterprise application servers. However, securing the deployment of the OSGi components, or bundles, proves to be a major challenge. The current approach consists in digitally signing the bundles(More)
Multicomplex numbers of order n have an associated trigonometry (multisine functions with n−1 parameters) leading to a natural extension of the sine-Gordon model. The parameters are constrained from the requirement of local current conservation. In two dimensions for n < 6 known integrable models (deformed Toda and non-linear sigma, pure affine Toda...)(More)
Cardiac alternans has been linked to the onset of ventricular fibrillation and ventricular tachycardia, leading to life-threatening arrhythmias. Here, we investigated the effects of stretch-activated currents (ISAC) on alternans using a physiologically detailed model of the ventricular myocyte. We found that increasing ISAC suppresses alternans if the(More)
The sodium/potassium ATPase (NKA) is essential for establishing the normal intracellular [Na+] and [K+] and transmembrane gradients that are essential for many cellular functions, including cardiac electrophysiology and contractility. Different NKA isoforms exhibit differential expression levels, cellular localization, and function in different tissues and(More)