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Achieving safe and readily accessible sources for cell replacement therapy in Parkinson's disease (PD) is still a challenging unresolved issue. Recently, a primitive neural crest stem cell population (hOMSC) was isolated from the adult human oral mucosa and characterized in vitro and in vivo. In this study we assessed hOMSC ability to differentiate into(More)
Human oral mucosa stem cells (hOMSC) are a recently described neural crest-derived stem cell population. Therapeutic quantities of potent hOMSC can be generated from small biopsies obtained by minimally invasive procedures. Our objective was to evaluate the potential of hOMSC to differentiate into astrocyte-like cells and provide peripheral neuroprotection.(More)
This review deals with the presently used techniques for reconstruction of full thickness lip defects that occur as a result of resection of malignant lesions of the lips. Reconstruction of full thickness defects of the lip is not an easy task. Since the lips have such centrally important aesthetic and functional roles, successful maintenance of these roles(More)
The use of myocutaneous flaps has revolutionized reconstructive surgery following tumor resections in the head and neck area. The platysma myocutaneous flap described almost a century ago has not received much attention, although it has been reported to be a satisfactory technique. Its successful use in 2 patients with squamous cell carcinoma of the tongue,(More)
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