Samira T. Rabie

  • Citations Per Year
Learn More
Some novel fused pyrimidine derivatives 5–14 were prepared starting with compound 4. Also, Ethyl 4-(2,5dimethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 2 was used for the preparation of some fused pyrimidine analogs 15–19. All synthesized compounds were evaluated for their antiviral activity against HAV virus by determination of(More)
N,N-Dimethyl-N'-(6-oxo-2-thioxo-1H-pyrimidine-4-yl)formamidine has been synthesized and introduced as a substituent in poly(vinyl chloride) (PVC) chains via a chemical reaction. Both the dimethyl derivative and the modified PVC have been characterized via spectroscopic analyses and their biological activities have been evaluated. Both IR and (1) H NMR(More)
epi-Androsterone 1 was converted into its hydrazone derivative through the reaction with hydrazine hydrate 80%. Hydrazonoandrostane derivative 2b reacted with hydrazonoyl halides in the presence of K(2)CO(3) forming the corresponding hydrazopyridazinoandrostane derivatives 6a-d. The 3β-acetyl-17-hydrazonoandrostane derivative 2b reacted with a halogen(More)
This study aimed at the synthesis of novel structurally promising steroidal heterocycles and to elucidate the potential role of these compounds as antibacterial agents. Epi-androsterone 1 reacted with CS2 and sodium hydride in dimethylsulfoxide to yield alpha-oxoketene dithiodisodium salt 2. The non-isolable salt 2 reacted with acetyl chloride, benzoyl(More)
  • 1