Samir Kanaan Nabhan

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BACKGROUND Umbilical-cord blood (UCB) is increasingly considered as an alternative to peripheral blood progenitor cells (PBPCs) or bone marrow, especially when an HLA-matched adult unrelated donor is not available. We aimed to determine the optimal role of UCB grafts in transplantation for adults with acute leukaemia, and to establish whether current(More)
BACKGROUND The importance of matching at the HLA C locus has not been well defined for unrelated umbilical-cord blood transplantation. The selection algorithm for umbilical-cord blood units generally considers intermediate resolution HLA typing at A and B and allele-level typing at DRB1. We aimed to establish the relative importance of additional matching(More)
Reduced fertility is one clinical manifestation among other well known Fanconi anemia features. Most recipients of allogeneic hematopoietic stem cell transplantation suffer from secondary infertility owing to gonadal damage from myeloablative conditioning. In order to evaluate the rate of pregnancy in Fanconi anemia transplanted patients, we performed a(More)
BACKGROUND Allogeneic stem cell transplantation is the only curative option for patients with hereditary bone marrow failure syndromes. Umbilical cord blood is an alternative source of stem cells for allogeneic transplantation. DESIGN AND METHODS This multicenter, retrospective study is based on data reported to the Eurocord Registry about patients with(More)
Although the relevance of dental intervention before transplant is recognized, many patients are undergoing transplantation without receiving dental care. The objective of this study was to identify the searching profile, access, and use of dental services by candidates to hematopoietic stem cell transplantation (HSCT), and the difficulties faced by those(More)
Central pontine myelinolysis (CPM) and extra-pontine myelinolysis (EPM) are different presentations of a demyelinating disorder of the brain more commonly associated with rapid correction of hyponatremia, spastic tetraparesia and pseudo-bulbar palsy. There are in the literature a few cases of CPM/EPM in patients without electrolyte disturbances. We report(More)
Juliane Morando1 Marcos Augusto Mauad2 Sérgio Costa Fortier1 Flavia Zattar Piazera1 Mair Pedro de Souza2 Claudia Oliveira2 Clarisse Machado2 Ederson Matos2 Wellington Moraes Azevedo2 Lisandro Lima Ribeiro1 Elenaide Coutinho Nunes1 Marco Antonio Bitencourt1 Daniela Cariranha Setúbal1 Vaneuza Moreira Funke1 Michel Michels de Oliveira1 Larissa Alessandra(More)
1Eurocord, Hôpital Saint-Louis, Paris, France; 2Hospital de Clinicas, Curitiba, Brazil; 3IRCCS Ospedale Bambino Gesù, Rome, University of Pavia, Pavia, Italy; 4Royal Children’s Hospital, Melbourne, Australia; 5Leiden University Medical Center, Leiden, The Netherlands; 6Hôpital Claude Huriez, Lille, France; 7Clinica di Oncoematologia Pediatrica, Padova,(More)
We analyzed risk factors influencing outcomes after related (R) human leukocyte antigen-identical cord blood transplantation (CBT) for 147 patients with malignancies reported to Eurocord-European Group for Blood and Marrow Transplantation. CBT has been performed since 1990; median follow-up was 6.7 years. Median patient age was 5 years. Acute leukemia was(More)