Samir B Lapsiwala

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OBJECTIVE We performed a biomechanical comparison of several C1 to C2 fixation techniques including crossed laminar (intralaminar) screw fixation, anterior C1 to C2 transarticular screw fixation, C1 to 2 pedicle screw fixation, and posterior C1 to C2 transarticular screw fixation. METHODS Eight cadaveric cervical spines were tested intact and after dens(More)
STUDY DESIGN AND OBJECTIVES A computed tomography (CT) study of 60 consecutive patients (120 sides) was performed to assess suitability for either transarticular or pedicle screw fixation. SUMMARY OF BACKGROUND DATA A C1 lateral mass and C2 pedicle screw fixation with a rigid cantilever beam system has been described. The anatomic constraints relevant for(More)
OBJECT Injury to the supplementary motor area (SMA) is thought to be responsible for transient motor and speech deficits following resection of tumors involving the medial frontal lobe. Because direct intraoperative localization of SMA is difficult, the authors hypothesized that functional magnetic resonance (fMR) imaging might be useful in predicting the(More)
PURPOSE Cerebral edema is responsible for significant morbidity and mortality in patients harboring malignant gliomas. To examine the role of inflammatory cells in brain edema formation, we studied the expression cyclooxygenase (COX)-2, a key enzyme in arachidonic acid metabolism, by microglia in the C6 rodent glioma model. EXPERIMENTAL DESIGN The(More)
OBJECT Hearing loss is the most common presenting symptom in patients who harbor a vestibular schwannoma (VS). Although mechanical injury to the cochlear nerve and vascular compromise of the auditory apparatus have been proposed, the exact mechanism of this hearing loss remains unclear. To test whether pressure on the cochlear nerve from tumor growth in the(More)
The management of adult-onset tethered cord syndrome (TCA) remains controversial, although the necessity of early surgery in children with TCS is well established. In this paper, we review the major publications that discuss the congenital tethered spinal cord (spina bifida occulta) presenting in adulthood. Data concerning acquired tethered cord from prior(More)
OBJECT The clinical diagnosis of cerebrospinal fluid (CSF) shunt malfunction can be challenging. In this prospective study, the authors evaluated a common method of interrogating shunts: the shunt tap; specifically, its ability to predict proximal malfunction. METHODS The authors performed standardized shunt taps in a consecutive series of cases involving(More)
BACKGROUND CONTEXT The treatment of compressive cervical myelopathy is, in general, a surgical endeavor. Surgery involves decompression, often with an accompanying fusion with stabilization. The length of the fusion can vary and the decision regarding length of fusion is not always clear. PURPOSE This study explores the fundamental principles regarding(More)
Intracerebral hemorrhage is bleeding into the brain parenchyma with possible extension into the ventricles and subarachnoid space. Each year, approximately 37,000 to 52,400 people suffer from intraparenchymal hemorrhage (IPH) in the United States. This rate is expected to rise dramatically in the next few decades as a result of the increasing age of the(More)
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