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The biophysical properties of small conductance Ca(2+)-activated K(+) (SK) channels are well suited to underlie afterhyperpolarizations (AHPs) shaping the firing patterns of a conspicuous number of central and peripheral neurons. We have identified a new scorpion toxin (tamapin) that binds to SK channels with high affinity and inhibits SK channel-mediated(More)
We have characterized tamulustoxin, a novel 35-amino-acid peptide found in the venom of the Indian red scorpion (Mesobuthus tamulus). Tamulustoxin was identified through a [125I]toxin I screen, designed to identify toxins that block voltage-activated potassium channels. Tamulustoxin has also been cloned by RT-PCR, using RNA extracted from scorpion venom(More)
This paper presents a low-complexity pitch estimation algorithm for packet loss concealment. The algorithm divides the pitch estimation into three stages with each additional stage providing further accuracy. Compared with a system based on G.711 Appendix I, the proposed algorithm requires approximately 32 percent fewer cycles on a DSP processor integrated(More)
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