Samar M Etman

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Piperine (PIP) is a phytopharmaceutical with reported neuroprotective potential in Alzheimer's disease (AD). Oral PIP delivery suffers from its hydrophobicity and pre-systemic metabolism. In this article, mono-disperse intranasal chitosan nanoparticles (CS-NPs) were elaborated for brain targeting of PIP. Formula optimization was based on particle size (PS),(More)
Alzheimer's disease (AD) is one of the most patient devastating central nervous system diseases with no curative therapy. An effective oral therapy with brain-targeting potential is required that is hampered by blood-brain barrier. Piperine (PIP) is a natural alkaloid with memory enhancing potentials. Oral PIP delivery suffers from its hydrophobicity and(More)
Ex Luton, an estrogen-free pill composed of 0.5 mg lynestrenol was given to 92 nonlactating women of proven fertility attending the Family Planning Clinic in the Misr Spinning and Weaving Company's Hospital at Mehalla-Kubra, Egypt. 695 cycles were given: 30 women received the pill for less than 6 cycles, and 62 for more than 6. 31 of the 62 continued the(More)
The tapered Lippes Loop D (LLD) is compared to the standard LLD to evaluate efficacy and termination events. The tapered device was designed with the intention of lowering the expulsion rate below the rate for women with standard Lippes Loops. The two devices were randomly assigned to 989 women in two studies. Expulsion rates for the tapered device were(More)
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