Samar K. Kassim

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—The main purpose of this paper is to show the use of formal concept analysis (FCA) as data mining approach for mining the common hypermethylated genes between breast cancer subtypes, by extracting formal concepts which representing sets of significant hypermethylated genes for each breast cancer subtypes, then the formal context is built which leading to(More)
—Hypomethylation of DNA have been associated with cancer in several investigations. Hypomethylated of CPG islands associated with promoters can affect the expression of genes to be more expressed. The Illumina GoldenGate Methylation Cancer Panel I can measure DNA methylation at 1505 CpG loci of 806 cancer related genes. A powerful tools to analysis the DNA(More)
The role of transforming growth factor-β (TGF-β) and nitric oxide (NO) in ovarian neoplasia is still not clear. We studied the expression of TGF-β by enzyme immunoassay, and nitrates (as a stable end product of NO) in 127 ovarian tissues (36 normal, 37 benign, and 54 malignant). Ploidy status and synthetic phase fraction (SPF) were also assessed by flow(More)
UNLABELLED The role of the tumor markers CA125 and CA72-4 has been evaluated in the diagnosis and management of ovarian cancer. Both markers were measured in 30 patients with proven epithelial ovarian cancer, 30 patients with benign pelvic masses and 30 normal women. CA125 and CA72-4 were measured using the luminometric immunoassay and immunoradiometric(More)
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