Samantha Timmons

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Noradrenergic projections to the cortex modulate a variety of cortical activities and calcium channels are one likely target for such modulation. We used the whole-cell patch-clamp technique to study noradrenergic modulation of barium currents in acutely dissociated pyramidal neurons from rat sensorimotor cortex. Extracellular application of specific(More)
Five out of twenty patients with vasotonic angina had frequent spontaneous attacks with dramatic ST-segment alterations. These attacks were consistently associated with an increase in platelet aggregates in coronary-sinus blood but not arterial blood. This increase in platelet aggregates during coronary-artery spasm suggests a potential causal role for the(More)
Prostacyclin (prostaglandin I2, PGI2), produced by the blood vessel wall is the most potent known inhibitor of platelet aggregation induced by such stimuli as ADP and thrombin. It binds to a specific platelet receptor and activates adenylate cyclase, raising the cyclic AMP level in platelets. This property can be important because platelets participate in(More)
We isolated 137 unique Australian brush-turkey (Alectura lathami) microsatellite sequences. Twenty-five loci when characterised in 24 individuals displayed 2–17 alleles per locus. Four loci were found to be Z-linked based on a complete lack of heterozygotes in females and sequence similarity to the chicken Z chromosome. Due to the small genetic distance(More)
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