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High protein concentration formulations are required for low-volume administration of therapeutic antibodies targeted for subcutaneous, self-administration by patients. Ultra-high concentrations… (More)
An automated method using biotinylated GroEL-streptavidin biosensors with biolayer interferometry (GroEL-BLI) was evaluated to detect the formation of transiently formed, preaggregate species in… (More)
OBJECTIVE To investigate neonatal morbidity and maternal complication rates with delivery body mass index (BMI) 60 or greater. METHODS This retrospective, multicenter cohort study included… (More)
Antibodies are molecules that exhibit diverse conformational changes on different timescales, and there is ongoing interest to better understand the relationship between antibody conformational… (More)