Samantha C Aust

Learn More
Figure 1. Serum reactivity to sec180 and NC16C regions of collagen XVII. Sera from 26 dementia and 24 Parkinson’s patients were screened for reactivity to recombinant sec180 or NC16C proteins by immunoblot. Reactivity was evaluated via densitometric analysis (NIH ImageJ) and values were normalized to the average density of negative control sera (assigned a(More)
Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by antibodies (IgG and IgE) targeting cell-substrate adhesion proteins. A variety of BP models suggest that autoantibody-dependent neutrophil degranulation is essential for blister formation. However, lesional biopsies reveal a predominance of eosinophils and few neutrophils. Our goal(More)
Increased levels of reactive oxygen species (ROS) such as superoxide anions and hydrogen peroxide have been reported in many cancer cells and they have been implicated in carcinogenesis and tumor progression. Antioxidant enzymes, such as Manganese Superoxide Dismutase (MnSOD or SOD2) and Glutathione Peroxidase-1 (GPx1), act coordinately to neutralize ROS.(More)
  • 1