Samah M. A. Issa

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Mutations that reduce expression or give rise to a Thr85Ser (T85S) mutation of Ca(2+)-CaM-dependent protein kinase kinase-2 (CaMKK2) have been implicated in behavioural disorders such as anxiety, bipolar and schizophrenia in humans. Here we report that Thr85 is an autophosphorylation site that endows CaMKK2 with a molecular memory that enables sustained(More)
UniCarb-DB is an experimental database consisting of structural information of O-linked and N-linked oligosaccharides and associated LC-MS/MS fragmentation data. This report illustrates how the database can be useful for future software development for the interpretation of glycomic mass spectrometric data. The information about rich fragmentation spectra(More)
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