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One goal of cell biology is to understand how cells adopt different shapes in response to varying environmental and cellular conditions. Achieving a comprehensive understanding of the relationship between cell shape and environment requires a systems-level understanding of the signalling networks that respond to external cues and regulate the cytoskeleton.(More)
Melanoma cells can adopt two functionally distinct forms, amoeboid and mesenchymal, which facilitates their ability to invade and colonize diverse environments during the metastatic process. Using quantitative imaging of single living tumor cells invading three-dimensional collagen matrices, in tandem with unsupervised computational analysis, we found that(More)
Data visualization is a fundamental aspect of science. In the context of microscopy-based studies, visualization typically involves presentation of the images themselves. However, data visualization is challenging when microscopy experiments entail imaging of millions of cells, and complex cellular phenotypes are quantified in a high-content manner. Most(More)
Today's educators are using mock trials and jury deliberations as a way to promote critical thinking and enhance communication skills. An English teacher at Tucson, Arizona's Cholla Magnet High School, incorporates mock trials and jury deliberations as a part of his class. The Center for the Management of Information, at the University of Arizona, developed(More)
The dynamics of signalling networks that couple environmental conditions with cellular behaviour can now be characterised in exquisite detail using live single-cell imaging experiments. Recent improvements in our abilities to introduce fluorescent sensors into cells, coupled with advances in pipelines for quantifying and extracting single-cell data, mean(More)
For our project, we have looked into the feasibility of clean coal technology as a potential source of energy for the production of electricity in cooperation with two other design teams. Although alternative energies such as solar and wind power have great potential, they are expensive to implement. On the other hand, clean coal power production is a(More)
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