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Prognostic role of minimal residual disease in mature B-cell acute lymphoblastic leukemia of childhood.
PURPOSE To study the prevalence of t(8;14) at diagnosis and the response kinetics to treatment of minimal residual disease (MRD) in B-cell acute lymphoblastic leukemia (B-ALL) patients and determineExpand
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Central nervous system complications during treatment of acute lymphoblastic leukemia in a single pediatric institution
Central nervous system (CNS) complications during treatment of childhood acute lymphoblastic leukemia (ALL) remain a challenging clinical problem. Outcome improvement with more intensive chemotherapyExpand
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Fungal Infections in Children With Cancer: A Prospective, Multicenter Surveillance Study
Background: Data on epidemiology and survival after fungal infections in patients with cancer are primarily based on studies in adults, whereas few data are available on children. Methods: AExpand
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A Phase II Trial on Alpha-Interferon α IFN) Effect in Patients with Monoclonal IgM Gammopathy
Waldenstrom's macroglobulinemia (WM) is an incurable disorder of B cells. Following occasional reports of response to α interferon (IFN) and in view of its effectiveness in hairy cell leukemia, weExpand
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Detection of prognostic factors in children and adolescents with Burkitt and Diffuse Large B‐Cell Lymphoma treated with the AIEOP LNH‐97 protocol
Burkitt lymphoma (BL) and Diffuse Large B‐Cell Lymphoma (DLBCL) account for most cases of non‐Hodgkin lymphoma (NHL) in childhood. We report the clinical characteristics, outcome and prognosticExpand
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Kinetics of humoral response to ALK and its relationship with minimal residual disease in pediatric ALCL
Kinetics of humoral response to ALK and its relationship with minimal residual disease in pediatric ALCL
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Minimal disseminated disease in high-risk Burkitt's lymphoma identifies patients with different prognosis.
PURPOSE To study minimal disseminated disease (MDD) in children with Burkitt's lymphoma (BL) and to determine its impact on prognosis. PATIENTS AND METHODS We established a simplified long-distanceExpand
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Mental retardation, congenital heart malformation, and myelodysplasia in a patient with a complex chromosomal rearrangement involving the critical region 21q22
The region 21q22 is considered crucial for the pathogenesis of both Down syndrome (DS) and the partial monosomy 21q syndrome. Haploinsufficiency of the RUNX‐1 gene, mapping at 21q22 is responsibleExpand
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Hb Rainier [beta145(HC2)Tyr-->Cys] in Italy. Characterization of the amino acid substitution and the DNA mutation.
A high oxygen affinity hemoglobin variant was identified in a 53-year-old male patient from Napoli (Italy), suffering from pulmonary thromboembolism and polycythemia. A detailed structuralExpand
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Postchemotherapy PET evaluation correlates with patient outcome in paediatric Hodgkin’s disease
AimTo evaluate the role of postchemotherapy FDG PET and compare it with other predictive factors in paediatric Hodgkin’s disease (HD).Materials and methodsIn this retrospective study, 98 paediatricExpand
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