Salma Haddad

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Some derivatives of hematoporphyrins are strongly retained by tumor tissue as compared to normal tissue, and exposure of these photosensitizers to radiation in the visible spectrum can cause serious biological damage. These properties have been exploited in the development of a new treatment for cancer termed photodynamic therapy (PDT). However, recent(More)
Lysosomes were separated from homogenized tissues of the submandibular gland of man and rat by means of ultracentrifugation. Besides acid phosphatase, the human lysosomes contained N-acetylglucosaminidase, α-mannosidase, α-glucosidase and β-glucuronidase. In addition to the above, the rat lysosomes showed β-xylosidase, α-fucosidase, β-glucosidase, and α-(More)
Mast cells undergo degranulation in response to various stimuli and rapidly release pre-formed mediators present in secretory granules, leading to immediate-type allergic reactions. Mast cell degranulation is commonly detected and quantified in vitro by measuring histamine or β-hexosaminidase released to culture medium. However, this type of assay cannot(More)
Elimadi, Aziz, and Pierre S. Haddad. Cold preservation-warm reoxygenation increases hepatocyte steady-state Ca21 and response to Ca21-mobilizing agonist. Am J Physiol Gastrointest Liver Physiol 281: G809–G815, 2001.— Although the role of Ca21 in liver transplantation injury has been the object of several studies, direct evidence for alterations in(More)
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