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  • Fiona A. Stennard, Mauro W. Costa, +12 authors Richard P. Harvey
  • Biology, Medicine
  • Development
  • 2005 (First Publication: 15 May 2005)
  • The genetic hierarchies guiding lineage specification and morphogenesis of the mammalian embryonic heart are poorly understood. We now show by gene targeting that murine T-box transcription factorExpand
  • Sally L. Dunwoodie, Melanie P. Clements, Duncan Burnaby Sparrow, Xin Sa, Ronald A. Conlon, Rosa S. P. Beddington
  • Biology, Medicine
  • Development
  • 2002 (First Publication: 1 April 2002)
  • A loss-of-function mutation in the mouse delta-like3 (Dll3) gene has been generated following gene targeting, and results in severe axial skeletal defects. These defects, which consist of highlyExpand
  • Sally M. Harrison, Denis Houzelstein, Sally L. Dunwoodie, Rosa S. P. Beddington
  • Biology, Medicine
  • Developmental biology
  • 2000 (First Publication: 1 November 2000)
  • We describe the identification, biochemical characterisation, and mutation of a novel mouse gene: Sp5. Sp5 encodes a protein having a C-terminal C(2)H(2) zinc finger domain closely related to that ofExpand