Sally Curtis

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Staphylococcus aureus bacteraemia (SAB) is commonly complicated by metastatic infection or relapse after treatment. Objectives. The study aim was to determine the role of bacterial, host, and management factors in development of complicated SAB. Methods. A prospectively-conducted observational study gathered data on predisposition, management and outcome of(More)
Multilocus sequence typing (MLST) of 48 methicillin-sensitive Staphylococcus aureus isolates from intravenous drug user abscesses/soft-tissue infections revealed 12 sequence types (STs) belonging to eight genetically distinct lineages. Only two novel STs were recovered (one isolate of each), indicating that isolates in this study were similar to those from(More)
BACKGROUND Esophagectomy and gastrectomy are associated with profound metabolic changes and significant postoperative morbidity. The aim of this prospective clinical study was to determine whether breath analysis can offer novel insight into the surgical metabolic response and identify biomarkers of postoperative complications, including lung injury. (More)
During noise-induced temporary threshold shift cytoplasmic vacuoles increase in the synaptic region of auditory hair cells. This structural change in the presynaptic region suggests that afferent synapses between hair cells and auditory nerve fibers fail during the period of threshold elevation, and that synaptic fatigue may play a major role.
ZR-75-1 human mammary cancer cells can be grown in serumfree medium in an estradiciand tamoxifen-sensitive manner. Growth occurs both in monolayer and suspension culture, al though serum is necessary during the initial plating of the cells in monolayer culture. Optimal stimulation of proliferation by estradiol occurs at 10~8 and 10~9 M. Tamoxifen alone(More)
The pattern of gap-junctional connections between cells in the vestibular neuroepithelium of the posterior semicircular duct of the alligator lizard are described based upon the study of freeze fracture replicas and ultrathin sections with a transmission electron microscope. Both type I and type II hair cells are coupled to adjacent supporting cells by a(More)