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Evolution of endocrine growth regulation: the insulin like growth factors (IGFs), their regulatory binding proteins (IGFBPs), and IGF receptors in fishes and other ectothermic vertebrates.
Use of MAR Elements to Increase the Production of Recombinant Proteins
- C. Gorman, S. Arope, Mélanie Grandjean, Pierre-Alain Girod, N. Mermod
- Cell Line Development
- 19 July 2009
The biopharmaceutical industry continues to face the challenge of producing large amount of recombinant proteins for use as therapeutics, and eighty percent of protein therapeutics in clinical… Expand
Molecular Characterization of a Human Matrix Attachment Region Epigenetic Regulator
Matrix attachment regions (MAR) generally act as epigenetic regulatory sequences that increase gene expression, and they were proposed to partition chromosomes into loop-forming domains. However,… Expand