Salim F. Haddad

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Inula graveolens is a poisonous annual plant of Mediterranean origin. The invasive nature of the plant suggests that it may possess phytotoxic activity. The aim of this study was to assess the ability of I. graveolens to inhibit the growth of different plants in Petri dish and to identify the main bioactive compounds. Bio-guided fractionation of the plant(More)
Biotransformation of methyl cholate using Aspergillus niger was investigated. This led to the isolation of two derivatives: methyl 3alpha,7alpha,12alpha,15beta-tetrahydroxy-5beta-cholan-24-oate identified as a new compound, and a known compound methyl 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate. The structure elucidation of the new compound was(More)
[NiCl2(C14H12N2)(H2O)] complex has been synthesized from nickel chloride hexahydrate (NiCl2·6H2O) and 2,9-dimethyl-1,10-phenanthroline (dmphen) as N,N-bidentate ligand. The synthesized complex was characterized by elemental analysis, infrared (IR) spectroscopy, ultraviolet-visible (UV-vis) spectroscopy and differential thermal/thermogravimetric analysis(More)
The title compound, [HgCl(2)(C(14)H(12)N(2))], consists of one 2,9-dimethyl-1,10-phenanthroline (dmphen) ligand chelating the Hg(II) ion and two chloride ligands coordinating to the Hg(II) ion, forming a distorted tetra-hedral environment. The dmphen ligand is nearly planar (r.m.s. deviation = 0.0225 Å). The dihedral angle between the normal to the plane(More)
The asymmetric unit of the title compound, (C(5)H(5)BrN)(2)[SnBr(6)], contains one cation and one half-anion. The [SnBr(6)](2-) anion is located on an inversion center and forms a quasi-regular octa-hedral arrangement. The crystal structure consists of two-dimensional supra-molecular layers assembled via hydrogen-bonding inter-actions of N-H⋯Br-Sn [D⋯A =(More)
The title salt, C20H26N3O2(+)·Cl(-), lies across a twofold crystallographic axis with the central N atom of the cation and the chloride anion sitting on this axis, Z' = 0.5. There is an intra-molecular hydrogen bond between the hy-droxy H atom and the imino N atom. The chloride anion and the cation are connected into chains along the a axis by an N-H⋯Cl(More)
The title compound, C25H26Cl2FN3O4S, contains two bio-active moieties (thio-barbituric acid and fluoro-quinolone). In the crystal, mol-ecules are linked via C-H⋯O and C-H⋯F hydrogen bonds, forming two-dimensional slab-like networks lying parallel to the bc plane. The benzene ring substituted by F and Cl atoms and the 4-chloro-butyl group seem to be partly(More)
The asymmetric unit of the title compound, (C(5)H(6)Br(2)N(3))(2)[SnBr(6)], contains one cation and one half-anion in which the Sn atom is located on a crystallographic centre of inversion and is in a quasi-octa-hedral geometry. The crystal structure is assembled via hydrogen-bonding inter-actions of two kinds, N(pyridine/amine)-H⋯Br-Sn, along with(More)
The asymmetric unit of the title salt, C(7)H(10)N(+)·Br(-), comprises two 2,6-dimethyl-pyridinium cations and two bromide anions. One cation and one anion are situated in general positions, while the other cation and the other anion lie on a crystallographic mirror plane parallel to (010). Each pair of ions inter-act via N-H⋯Br and C-H⋯Br hydrogen bonding,(More)
In the title mol-ecular salt, C(10)H(10)N(2) (2+)·2Br(-), the dihedral angle between the aromatic rings is 20.83 (14)° and the N-H groups have a transoid conformaton [N-C-C-N = 158.5 (3)°]. In the crystal, the cations are linked to the anions by two N-H⋯Br and five C-H⋯Br hydrogen bonds, generating corrugated sheets incorporating R(2) (1)(7), R(4) (2)(10),(More)