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The inhibitory effects of flavonoids on monoamine oxidases (MAOs) have attracted great interest since alterations in monoaminergic transmission are reported to be related to neurodegenerative diseases such as Parkinson's and Alzheimer's diseases and psychiatric disorders such as depression and anxiety, thus MAOs may be considered as targets for the(More)
The use of planar microelectrode arrays allows one to register the electrophysiological activity of cultured neurons under virtual non-invasive conditions for a long period of time (i.e. hours). Several neural networks in the developing Central Nervous System are spontaneously active and such behavior seems to play an important role in subsequent(More)
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