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Squamous Cell Carcinoma of the Vulva: A Subclassification of 97 Cases by Clinicopathologic, Immunohistochemical, and Molecular Features (p16, p53, and EGFR)
Squamous cell carcinomas (SCCs) of the vulva develop through human papilloma virus (HPV)-associated or HPV-independent pathways, but the relationship between pathogenesis, classification, andExpand
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Expression of matrix metalloproteinases (MMPs) in cultured hepatocellular carcinoma (HCC) cells and surgically resected HCC tissues.
Matrix metalloproteinases (MMPs) relate to the growth and infiltration of cancer cells, but the frequency and amount of their expression are not yet fully examined in hepatocellular carcinoma.Expand
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Decreased survival in EGFR gene amplified vulvar carcinoma.
OBJECTIVE We undertook an extensive molecular characterization of the epidermal growth factor receptor (EGFR) gene in vulvar squamous cell carcinomas to investigate EGFR mutation and/or genomicExpand
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Antiproliferative effects of 5‐fluorouracil and interferon‐alpha in combination on a hepatocellular carcinoma cell line in vitro and in vivo
Background and Aim:  We investigated the antiproliferative effects of interferon‐alpha (IFN‐α) and 5‐fluorouracil (5‐FU) in combination on a hepatocellular carcinoma (HCC) cell line.
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Antiproliferative Effects of Interferon-αCon1 on Ovarian Clear Cell Adenocarcinoma In vitro and In vivo
Purpose: We examined the antiproliferative effect of IFN-αCon1 and its mechanism on ovarian clear cell adenocarcinoma in vitro and in vivo. Experimental Design: (a) The effects of IFN-αCon1 onExpand
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Interferon-alphaCon1 suppresses proliferation of liver cancer cell lines in vitro and in vivo.
BACKGROUND/AIMS We investigated the effects of consensus interferon (IFN-alphaCon1), a nonnaturally occurring type I interferon with higher specific activity than other type I IFNs, on the growth ofExpand
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Growth inhibitory effects of pegylated IFN α‐2b on human liver cancer cells in vitro and in vivo
Abstract: Purpose: We investigated the effects of pegylated IFN‐α2b (PEG‐IFN‐α2b) on the growth of human liver cancer cells.
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Growth inhibitory effects of pegylated IFN alpha-2b on human liver cancer cells in vitro and in vivo.
PURPOSE We investigated the effects of pegylated IFN-alpha2b (PEG-IFN-alpha2b) on the growth of human liver cancer cells. METHODS The effect of PEG-IFN-alpha2b on the proliferation of 13 liverExpand
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Overexpression of the myc target gene Mina53 in advanced renal cell carcinoma
The myc target gene Mina53 was reported to be overexpressed in esophageal cancer with a poor prognosis. The purpose of the present study was to examined Mina53 expression and its relationship toExpand
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Interferon-αCon1 suppresses proliferation of liver cancer cell lines in vitro and in vivo
Background/Aims We investigated the effects of consensus interferon (IFN-αCon1), a nonnaturally occurring type I interferon with higher specific activity than other type I IFNs, on the growth ofExpand
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