Saima Alvi

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OBJECTIVE To document the demographics and outcome of children with Acute Myeloid Leukemia (AML) treated at a tertiary care facility of Pakistan. METHODS A retrospective study was conducted at Aga Khan University on children (less than 15 years) diagnosed to have AML between January 2000 to May 2007.Total 40 cases were diagnosed out of which 37 charts(More)
The outcome of children with kidney tumors has significantly improved in the last two decades in the developed world but not in resource poor countries. We share our ten years experience from a single institution of Pakistan. Records of 23 children with kidney tumors were reviewed for demographics, presenting features, staging work-up and outcome. There(More)
There is no consensus on the immunization guidelines for immunocompromised children. Some recommendations are, however, available for children living in developed countries. The spectrum of infectious diseases is different in resource-poor countries. Vaccinations against some of these infections are not a part of the immunization schedule for children(More)
Pain Res Manag Vol 20 No 3 May/June 2015 e29 visits or busy hospital admissions. However, due to important advancements in therapeutic regimes and changes to healthcare systems, these youth now spend less time hospitalized and more time at home. This means youth with cancer and their families are increasingly responsible for managing cancer-associated pain(More)
BACKGROUND Despite the success of central nervous system (CNS) directed therapy in pediatric acute lymphoblastic leukemia (ALL), relapse involving the CNS continues to be observed in 5-10% of children when utilizing standard intrathecal prophylactic chemotherapy. While most pediatric ALL treatment protocols mandate regular lumbar punctures (LP) for the(More)
A 10-year-old girl with trisomy 21 and complex congenital heart disease presented with acute lymphoblastic leukemia. Her chemotherapy required modifications due to poor baseline cardiac status and a mechanical prosthetic heart valve that was dependent on anticoagulation. We describe our management including the use of low-molecular-weight heparin as(More)
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