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- Prabhakar K. Ranjekar, Ashwini Hinge, +6 authors Sahebarao Prabhu Mahadik
- Psychiatry Research
- 2003
Oxidative stress-mediated cell damage has been considered in the pathophysiology of schizophrenia. Abnormal findings have often been considered related to differences in ethnicity, life style,… (More)
- Mohammad M H Khan, Denise R Evans, Vijayasudha Gunna, Russell E. Scheffer, Vinay V Parikh, Sahebarao Prabhu Mahadik
- Schizophrenia Research
- 2002
Abnormal membrane phospholipid essential polyunsaturated fatty acid (EPUFA) metabolism (i.e., reduced incorporation into phospholipids and increased breakdown) has been suggested to contribute to the… (More)
- Chandramohan G. Wakade, Sahebarao Prabhu Mahadik, Jennifer L Waller, F. C. Alex Chiu
- Journal of neuroscience research
- 2002
Schizophrenia has been treated effectively with atypical neuroleptics without serious side effects. We have shown previously that long-term treatment with atypical neuroleptics is correlated with an… (More)
- Anilkumar Pillai, Anvita Anand Kale, +4 authors Sahebarao Prabhu Mahadik
- The international journal of…
- 2010
Brain-derived neurotrophic factor (BDNF), which plays an important role in neurodevelopmental plasticity and cognitive performance, has been implicated in neuropsychopathology of schizophrenia. We… (More)
- Peter Buckley, Sahebarao Prabhu Mahadik, Anilkumar Pillai, Alvin V. Terry
- Schizophrenia Research
- 2007
Neurotrophins have established roles in neuronal development, synaptogenesis, and response to stress/anxious stimuli. Moreover, these agents are neuromodulators of monoaminergic, GABAergic, and… (More)
- Sahebarao Prabhu Mahadik, Sukdeb Mukherjee
- Schizophrenia Research
- 1996
There is increasing evidence that free radical-mediated CNS neuronal dysfunction is involved in the pathophysiology of schizophrenia. Free radicals (oxyradicals, such as superoxide, hydroxyl ions,… (More)
- Meena Arvindakshan, Madhav R. Ghate, Prabhakar K. Ranjekar, Denise R Evans, Sahebarao Prabhu Mahadik
- Schizophrenia Research
- 2003
Reduced levels of membrane essential polyunsaturated fatty acids (EPUFAs), namely, arachidonic acid (AA), eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acids (DHAs),… (More)
- Meena Arvindakshan, Sandhya L. Sitasawad, Vijay B Debsikdar, Madhav R. Ghate, Sahebarao Prabhu Mahadik
- Biological Psychiatry
- 2003
BACKGROUND
Reduced levels of membrane essential polyunsaturated fatty acids (EPUFAs) and increased levels of lipid peroxidation products (thiobarbituric acid reactive substances; TBARS) have been… (More)
- Vinay V Parikh, Mohammad M H Khan, Sahebarao Prabhu Mahadik
- Journal of psychiatric research
- 2003
Typical and atypical antipsychotics significantly differ in their neurotransmitter receptor affinity profiles, and their efficacy and side effects in schizophrenic patients. Typical antipsychotics… (More)
- Peter Buckley, Anilkumar Pillai, David C. Evans, Edna M. Stirewalt, Sahebarao Prabhu Mahadik
- Schizophrenia Research
- 2007
There is much interest, derived from current neurochemical, genetic, and therapeutic research, in the role of brain neurotrophins in schizophrenia. Neurotrophins play key roles in neuronal… (More)